ORAL BIO-COMPLEX Description
A clinical trial of oral hygiene remedy DENOVA Oral Bio-Complex was conducted at the Department of Prevention of Dental Diseases, Moscow State University of Medicine and Dentistry. BRIEFLY and PRELIMINARILY: 1. The anti-inflammatory efficacy of the use of DENOVA Oral Bio-Complex is 52.0% 2. It should be noted that gingival sulcus bleeding in patients at the end of study was established only in isolated cases. The average API index at the final inspection was 0.5 Â± 0.5 and was 98.3% below the reference value! 3. The use of hygiene remedy for a month helped in whitening the color of teeth in most patients. The whitening effect was also characterized by an effective reduction in the number of dense pigmented plague (âsmokerâs plaqueâ) in the majority of the patients. It is necessary for a dentist to bring this to the attention of every smoking patient. 4. Control dental examinations revealed no pronounced changes in the oral mucosa characterized as signs of irritant or allergenic effect of DENOVA Oral Bio-Complex 5. At the final examination conducted 30 days after applying DENOVA Oral Bio-Complex, positive changes in the composition of the microflora of the gingival sulcus biofilms were revealed. They were characterized by a significant decrease in the concentration of parodontopathogenic bacteria of the species Prevotella intermedia, by reduced frequency in secretion of Porphyromonas gingivalis, as well as by complete disappearance of fusobacterium. 6. Results obtained suggest that the active components of DENOVA Oral Bio-Complex have antibacterial action against members of parodontopathogenic microflora (mainly gram-negative anaerobic bacteria) without negatively influencing the composition of the normal microflora of the gingival sulcus biofilm. 7. Thus, the use of medicated product DENOVA Oral Bio-Complex can be recommended to patients with inflammatory periodontal diseases in order to improve oral hygiene and eliminate inflammation and bleeding of gums.
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